The belief is widespread that mixed eye-hand dominance, i.e., the tendency for eye and hand preference to be opposite sided, is a cause of reading disability, nervousness and behavior problems in children. A number of published studies report conflicting results. Further evidence bearing on this question was obtained through a survey of an elementary school population of 101 boys and 90 girls from kindergarten to Grade VI. Age ranged from 6 to 11 yrs. The population ranged above average in general ability and any reading disability which existed in it was not due to intellectual incapacity. The tests for eye dominance were: Sighting a dot through a half-inch hole with each eye; sighting with the Parson manoptoscope; sighting through a 1/4-inch aperture at an Easter-egg peep-show to discover eye used in fixating on pictures. The tests of handedness were simple: picking up scissors and cutting; writing name; and picking up and tossing a ball. Stanford Reading Achievement scores were available for all subjects. The % of mixed dominance at all age levels was 30.6%. There was no clear cut developmental tendency from one age group to the next. Most studies report a decrease in left-handedness with age, and there is some slight evidence of support of this in the present data. But there was no similar decrease with age in left-eyedness; rather, a considerable increase in the 11-yr. group. Right-eyed children showed more consistency in all the eye tests than did left-eyed children. There were a substantial number of right-eyed children writing with the left hand. 22 subjects were having reading disability. About 45% of these were of the mixed dominant type. But these subjects represented < 1/2 of all the mixed dominant types in the population studied. It is concluded, that mixed dominance is not a prevailing condition in reading disability, and far less a dominant causal factor in the majority of disability cases.