Cyclic nucleotide phosphodiesterase inhibitors prevent aggregation of human platelets by raising cyclic amp and reducing cytoplasmic free calcium mobilization
- 1 March 1987
- journal article
- research article
- Published by Elsevier in Thrombosis Research
- Vol. 45 (5), 477-484
- https://doi.org/10.1016/0049-3848(87)90310-0
Abstract
No abstract availableKeywords
This publication has 17 references indexed in Scilit:
- Inhibition of human platelet cyclic AMP phosphodiesterase and of platelet aggregation by a hemisynthetic flavonoid, amentoflavone hexaacetateBiochemical Pharmacology, 1986
- Responses to adenosine diphosphate in human platelets loaded with the fluorescent calcium indicator quin2.The Journal of Physiology, 1985
- Using quin2 in cell suspensionsCell Calcium, 1985
- Cyclic amp inhibits platelet activation independently of its effect on cytosolic free calciumBiochemical and Biophysical Research Communications, 1985
- Cytoplasmic Ca2+ in platelets is controlled by cyclic AMP: Antagonism between stimulators and inhibitors of adenylate cyclaseBiochemical and Biophysical Research Communications, 1984
- Effect of cyclic amp on cytoplasmic free calcium in human platelets stimulated by thrombin: Direct measurement with quiǹ2Thrombosis Research, 1983
- Tissue and substrate specificity of inhibition by alkoxy-aryl-lactams of platelet and arterial smooth muscle cyclic nucleotide phosphodiesterases relationship to pharmacological activityBiochemical and Biophysical Research Communications, 1983
- The cytoplasmic concentration of free calcium in platelets is controlled by stimulators of cyclic AMP production (PGD2, PGE1, forskolin)Biochemical and Biophysical Research Communications, 1983
- HL 725, an extremely potent inhibitor of platelet phosphodiesterase and induced platelet aggregation in vitroLife Sciences, 1982
- Role of cyclic AMP in the inhibition of human platelet aggregation by quercetin, a flavonoid that potentiates the effect of prostacyclinBiochemical Pharmacology, 1982