Application of volume‐selected, two‐dimensional multiple‐quantum editing in vivo to observe cerebral metabolites
- 1 December 1990
- journal article
- research article
- Published by Wiley in Magnetic Resonance in Medicine
- Vol. 16 (3), 496-502
- https://doi.org/10.1002/mrm.1910160317
Abstract
The volume selection technique SPACE has been combined with a two-dimensional multiple-quantum editing sequence to uniquely detect certain J-coupled cerebral metabolites. In vivo results demonstrating edited glutamate/glutamine and lactate from 0.4 ml of a rat's brain at 4.7 T are presented. The sequence was optimized to balance multiple-quantum generation and signal loss due to T2 relaxation. Without due regard to T2 relaxation little signal is observed. © 1990 Academic Press, Inc.Funding Information
- National Health and Medical Research Council
- Australian Research Council
- Queensland Cancer Fund
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