Comparison between Weight Reduction on a High-Calorie, High-Fat Diet and on an Isocaloric Regimen High in Carbohydrate

Abstract

THE claim has been recently publicized that fat *- can be eaten ad libitum and still induce weight loss in obese subjects whereas carbohydrate in isocaloric amounts is held to stimulate the deposition of fat and hence weight gai-.^{1 2 3 4} The original report described losses of 4.1 to 24.5 kg. (9 to 54 pounds) in one to six months in 20 obese men on the high-fat regimen.¹ In a trial of the diet on a few patients in the Combined Endocrine Clinic of the Presbyterian Hospital the fact was confirmed that weight was lost, but the suspicion was left that the . . .