Emergence of Antibiotic-Resistant Bacteria

Abstract

Biologic and Biochemical Properties of Antibiotic-Resistant StrainsComparisons of Sensitive and Resistant Strains of the Same SpeciesAlthough the mechanisms involved in the development of antibiotic resistance will not be considered in detail, some studies designed to elucidate the problem and some illustrations of differences between sensitive and resistant strains may be mentioned. Bellamy and Klimek⁴⁷³ noted that a penicillin-resistant variant of Staph. aureus grew more slowly than its sensitive parent culture and also lost its ability to grow anaerobically. They could not increase significantly the resistance of strains of Str. faecalis, Str. mastitidis or Clostridium welchii by similar methods. . . .