Computerized Tomography in the Study of West's Syndrome

Abstract

Children [37] presenting with West''s syndrome were studied by computerized tomography scanning. An abnormality consisting of diffuse cerebral atrophy, predominating in the fronto-temporal region, was demonstrated in 30 cases. The abnormality was sometimes associated with calcification (tuberous sclerosis) or malformation (agenesis of the corpus callosum). The etiology of this atrophy and its relationship to clinical and EEG signs were discussed. Computerized tomography scanning was recommended for children with West''s syndrome to distinguish between primary and secondary cases, and for greater prognostic accuracy.