Renal Reabsorption of Calcium Through Its Inhibition by Various Chemical Agents

Abstract

Active reabsorption of Ca is depressed by the metabolic inhibition produced by phlorizin, dinitrophenol, and sodium azide and by the simultaneous reabsorption of strontium. Na and K excretion were relatively unaffected by these agents and Diamox, which increases Na and K excretion greatly had no effect on Ca reabsorption. Pentobarbital anesthesia greatly enhanced Ca, Na, and phosphate excretion but did not affect K or water excretion.