Frequent shedding of human herpesvirus 6 in saliva
- 1 February 1990
- journal article
- research article
- Published by Wiley in Journal of Medical Virology
- Vol. 30 (2), 128-130
- https://doi.org/10.1002/jmv.1890300209
Abstract
We have previously reported the isolation of HHV-6 from saliva samples. Because these isolations were made in PHA-stimulated lymphocytes from healthy adults, which may occasionally contain endogenous HHV-6, it was desirable to repeat this work using cord blood lymphocytes. In this study 18 isolations of viruses provisionally characterized as HHV-6 were made from 19 saliva samples by centrifugally enhanced inoculation into PHA-stimulated cord blood lymphocytes. HHV-6 was not found in 10 pernasal aspirates, 50 endocervical swabs, or 30 male urethral swabs. It is concluded that HHV-6 is usually present in the saliva of most adults and that this affords a possible explanation of the high infection rate with this virus in young children.Keywords
This publication has 13 references indexed in Scilit:
- Centrifugal enhancement of human immunodeficiency virus (HIV) and human herpesvirus type 6 (HHV-6) infection in vitroJournal of Virological Methods, 1989
- The value of MLA 144 culture fluid for the isolation of human immunodeficiency virusImmunology & Cell Biology, 1989
- Human herpes virus type 6 (HHV-6) and its in vitro effect on human immunodeficiency virus (HIV).Journal of Clinical Pathology, 1988
- Utilization of human hematopoietic cell lines for the propagation and characterization of HBLV (human herpesvirus 6)International Journal of Cancer, 1988
- HIGH PREVALENCE OF ANTIBODY TO HUMAN HERPESVIRUS-6 AND SEROCONVERSION ASSOCIATED WITH RASH IN TWO INFANTSThe Lancet, 1988
- HUMAN HERPESVIRUS 6 AND EXANTHEM SUBITUMThe Lancet, 1988
- Characteristics of Human Herpesvirus-6The Journal of Infectious Diseases, 1988
- ANTIBODY TO HUMAN HERPESVIRUS 6 IN SALIVAThe Lancet, 1988
- A NOVEL LYMPHOTROPIC HERPESVIRUSThe Lancet, 1987
- Isolation of a New Virus, HBLV, in Patients with Lymphoproliferative DisordersScience, 1986