Contributions to the Study of Brain Metabolism

Abstract

Experiments show that the glycogen content of brain tissue, which is small, does not diminish on anaerobic incubation of the tissue, nor does it alter appreciably when free access of O2 is ensured; in the latter case, there is a rapid disappearance of preformed lactic acid. The opinion is advanced that lactic acid of the brain arises from blood glucose and not from any precursor preexisting in the tissue.