Characteristic Individual Electrophoretic Patterns in Humans.

Abstract

Detailed examination of the contours and fine architecture of the electrophoretic patterns, of the shape, symmetry or asymmetry, and of the width of each protein peak in 1250 electrophoretic plasma analyses of 440 individuals reveals valuable information which cannot be obtained by calculating the relative amts. of the protein components alone. Characteristic individual electrophoretic patterns of the plasma proteins have been observed in numerous individuals, which remain constant in the same person over long periods of time, although the composition of the plasma fractions may vary considerably during this period. The distinguishing characteristics are independent of sex and age. In healthy persons they are confined mainly to the alpha-globulins. With a few exceptions they are not related to the disease state in patients.