A Comparative Trial of Lorazepam and Diazepam

Abstract

Lorazepam is a psychotropic agent of the benzodiazepine class which has an action qualitatively similar to, but more potent than, chlordiazepoxide and diazepam. In animals lorazepam is about twenty times as potent as chlordiazepoxide as an anti-anxiety agent and 10–50 times as potent as an anticonvulsant. In addition it has been reported as having an effective amnesic effect in higher doses in animals.