Isolation of Gram Quantities of Configurational Isomers of Cyclic Nitrosamines by Preparative Liquid Chromatography
- 1 January 1979
- journal article
- research article
- Published by Taylor & Francis in Journal of Liquid Chromatography
- Vol. 2 (8), 1219-1228
- https://doi.org/10.1080/01483917908060132
Abstract
Substituted cyclic nitrosamines, e.g., 2,6-dimethyl-N-nitrosomorpholine and 3,5-dimethyl-N-nitrosopiperidine [potential carcinogens] are separable into their component configurational isomers by preparative hplc [high power liquid chromotography]. Gram quantities of the individual isomers sufficient for animal testing were obtained. The identification of contaminants in commercial 2,6-dimethylmorpholine of purported 99% is discussed.This publication has 4 references indexed in Scilit:
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