Tissue-specific expression of mRNAs for dipeptidyl carboxypeptidase isoenzymes.
- 1 July 1982
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 79 (14), 4295-4297
- https://doi.org/10.1073/pnas.79.14.4295
Abstract
The MW of newly synthesized dipeptidyl carboxypeptidase (angiotensin-converting enzyme; polypeptide primed in a reticulocyte lysate by poly(A)-containing RNA from mature rabbit testis was only about 65% that of the immunologically related species programmed by pulmonary RNA. Furthermore, in contrast to the pulmonary RNA-dependent product, the synthesis of this testicular protein was not directed by RNA from testes of immature animals. A shorter polypeptide chain and pubertal expression, the structural and regulatory properties that distinguish the testicular dipeptidyl carboxypeptidase isozyme are probably determined pretranslationally.Keywords
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