Isolated Granulomas in Hodgkin's Disease

Abstract

THE occasional occurrence of a granulomatous process in tissues involved by Hodgkin's disease has long been recognized.^{1 , 2} However, the presence of noncaseating tubercle-like granulomas within otherwise uninvolved organs of patients with Hodgkin's disease is not well known. To date, only isolated cases of this finding have been reported^{3 4 5 6} and have been thought by some to represent coexistent sarcoidosis.⁵ Of great concern to us has been the interpretation of these granulomas as additional foci of Hodgkin's disease in patients referred to this institution.We have encountered this, as yet unexplained, phenomenon in a large number of patients with Hodgkin's disease studied . . .