Treatment of Mice Infected with Methicillin-Resistant Staphylococcus aureus
- 1 January 1982
- journal article
- research article
- Published by S. Karger AG in Chemotherapy
- Vol. 28 (4), 294-297
- https://doi.org/10.1159/000238093
Abstract
The efficacy of six antistaphylococcal agents for the treatment of experimental methicillin-resistant Staphylococcus aureusinfections was studied. Mice were injected intravenously with ≈ 5 × 108 methicillin-resistant S. aureus and treated by intraperitoneal administration of antimicrobics. Vancomycin, trimethoprim-sulfamethoxazole and rifampin therapies resulted in increased survival when compared to untreated controls.Keywords
This publication has 6 references indexed in Scilit:
- Methicillin-Resistant Staphylococcus aureus: Introduction and Spread Within a HospitalAnnals of Internal Medicine, 1980
- Treatment of experimental staphylococcal infections: effect of rifampin alone and in combination on development of rifampin resistanceAntimicrobial Agents and Chemotherapy, 1980
- An Outbreak of Infections Caused by Strains of Staphylococcus aureus Resistant to Methicillin and Aminoglycosides. I. Clinical StudiesThe Journal of Infectious Diseases, 1979
- Resistance of Staphylococcus aureus to Semisynthetic Penicillins and CephalothinThe Journal of Infectious Diseases, 1977
- Clinical, epidemiologic and bacteriologic observations of an outbreak of methicillin-resistant staphylococcus aureus at a large community hospitalAmerican Journal Of Medicine, 1976
- CHARACTERISTICS OF METHICILLIN-RESISTANT STAPHYLOCOCCIJournal of Bacteriology, 1964