An Evaluation of the Technic and Results of the Radioactive Di-Iodo-Fluorescein Test for the Localization of Intracranial Lesions

Abstract

340 patients suspected of having central nervous system tumors were examined by the radio-active di-iodo-fluorescein test. Detection of the lesion was 95% accurate, localization being more precise than with electro-encephalography or pneumography when verification was obtained at surgery or autopsy. The cellularity and vascular patternof the tumor are important factors in the affinity of the radiodye for tumor tissue. The authors conclude that "the radioactive di-iodo-fluorescein test is a simple, safe, painless and reliable method for the localization and diagnosis of brain tumors, and one that should grow in value as increasingly more sensitive detection equipment and newer radiodyes become available.".