Activation parameters for intramolecular nucleophilic substitution by carbanions—the insignificant effect of ring strain on cyclisation rates

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Abstract
Activation parameters for the cyclisation of bis-sulphonyl-stabilised carbanions to bis-sulphonylcycloalkanes have been determined; cyclopropanes form nearly a million-fold faster than cyclobutanes and ring strain is a negligible factor in determining reactivity.