Urticaria Due to Drugs of the Digitalis Series

Abstract

IN 1936 Romano and Geiger¹ described a case in which eosinophilia was evidently attributable to digitalis medication, and reference was made to two similar previous reports.^{2 , 3} The familiar nausea, vomiting and diarrhea accompanying digitalis administration are generally regarded as local or systemic toxic expressions of digitalis excess and may sometimes represent an idiosyncrasy but not an atopic reaction to the drug. In fact, true allergy to digitalis or allied drugs has rarely been documented, but Cohen and Brodsky⁴ reported a convincing case and reviewed the scant medical literature on the subject in 1940. The case described below appears to have . . .