Hyperuricemia in Hyperparathyroidism

Abstract

HYPERURICEMIA has been reported to occur in a wide variety of metabolic abnormalities. The demonstration of elevated serum uric acid levels in such diverse pathologic states as acromegaly,¹ myxedema,² hypoparathyroidism,³ pseudopseudohypoparathyroidism,⁴ diabetes mellitus⁵ and essential hypercholesterolemia⁶ defies a common physiologic explanation. Our recent experiences with hyperparathyroid subjects suggests that the association of hyperuricemia and functioning parathyroid adenomas is not infrequent. The further demonstration of a surprising incidence of gout in these subjects bears emphasis. It is the purpose of this paper to report the incidence of these combined abnormalities in a small group of patients, the effect of removal of . . .