Combination Therapy for Hepatitis C Infection

Abstract

About 4 million people in the United States and probably more than 100 million people worldwide are infected with the hepatitis C virus (HCV).¹ The majority have no symptoms, although they can transmit this blood-borne virus to others. People who have been infected for decades may first come to medical attention because of complications related to advanced liver disease. Ironically, the public health implications of HCV infection have only recently been widely appreciated, as a result of epidemiologic studies that pointed out the magnitude of infection and an alarming increase in morbidity and mortality due to HCV-related disease.In the . . .