Effect of beta-adrenergic stimulation on whole-body and abdominal subcutaneous adipose tissue lipolysis in lean and obese men
Open Access
- 5 December 2007
- journal article
- clinical trial
- Published by Springer Nature in Diabetologia
- Vol. 51 (2), 320-327
- https://doi.org/10.1007/s00125-007-0866-y
Abstract
Obesity is characterised by increased triacylglycerol storage in adipose tissue. There is in vitro evidence for a blunted beta-adrenergically mediated lipolytic response in abdominal subcutaneous adipose tissue (SAT) of obese individuals and evidence for this at the whole-body level in vivo. We hypothesised that the beta-adrenergically mediated effect on lipolysis in abdominal SAT is also impaired in vivo in obese humans.Keywords
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