Epidermolysis bullosa simplex associated with muscular dystrophy with recessive inheritance

Abstract

† Epidermolysis bullosa with unusually severe clinical features was associated with progressive muscular dystrophy in two siblings. Light and electron microscopic examination revealed an intraepidermal cleavage confirming that this mechanobullous disease belonged to the epidermolysis bullosa simplex group. This may represent a new disease entity inherited in an autosomal-recessive fashion. (Arch Dermatol1988;124:551-554)