A DISTINCTIVE CELL CONTACT IN THE RAT ADRENAL CORTEX
Open Access
- 1 April 1972
- journal article
- Published by Rockefeller University Press in The Journal of cell biology
- Vol. 53 (1), 148-163
- https://doi.org/10.1083/jcb.53.1.148
Abstract
Extensive cell contacts which resemble septate junctions occur between cells in the three major zones of the rat adrenal cortex. Characteristically, they extend between small intercellular canaliculi and the periendothelial space, frequently interrupted by gap junctions and rarely by desmosomes. Zonulae occludentes have not been identified in the adrenal cortex. Along this distinctive cell contact, the cell membranes of apposing cells are separated by 210-300 a bisected by irregularly spaced 100-150-A extracellular particles which are often circular in profile. In lanthanum preparations, these particles appear to form a continuous chain throughout the intercellular space and are visualized as an alveolate structure in sections parallel to the plane of the cell membrane. The cell membrane in the area of septate-like contact does not differ from nonjunctional areas of the cell membrane in freeze-fracture replicas. The cell contact retains its integrity after cell dispersion and after the separation of cell membranes from disrupted cells. The intercellular particles also persist after brief extraction in lipid solvents. Besides adherence, possible functions of this adrenal contact include maintenance of the width of the extracellular space, the provision of channels between intercellular canaliculi and the bloodstream, and utilization as cation depots. Similar structures are also present between adrenal cortical cells of several other species and between interstitial cells of the testis. This type of cell contact may, in fact, be a typical feature of steroid-hormone-secreting tissues in vertebrates.Keywords
This publication has 27 references indexed in Scilit:
- HIGH-YIELD PREPARATION OF ISOLATED RAT LIVER PARENCHYMAL CELLSThe Journal of cell biology, 1969
- BASAL JUNCTIONS AT SYNAPTIC ENDINGS OF TURTLE VISUAL CELLSThe Journal of cell biology, 1969
- Occurrence of repeating septate subunits between apposed cellular membranesExperimental Cell Research, 1968
- LIGHT AND ELECTRON MICROSCOPIC STUDIES ON THE ZONATION OF THE ADRENAL CORTEX IN ALBINO RATSEndocrinologia Japonica, 1968
- FUNCTIONS OF COATED VESICLES DURING PROTEIN ABSORPTION IN THE RAT VAS DEFERENSThe Journal of cell biology, 1967
- HEXAGONAL ARRAY OF SUBUNITS IN INTERCELLULAR JUNCTIONS OF THE MOUSE HEART AND LIVERThe Journal of cell biology, 1967
- Fracture faces of frozen membranes.Proceedings of the National Academy of Sciences, 1966
- THF EARLY STAGES OF ABSORPTION OF INJECTED HORSERADISH PEROXIDASE IN THE PROXIMAL TUBULES OF MOUSE KIDNEY: ULTRASTRUCTURAL CYTOCHEMISTRY BY A NEW TECHNIQUEJournal of Histochemistry & Cytochemistry, 1966
- A MODIFIED PROCEDURE FOR LEAD STAINING OF THIN SECTIONSThe Journal of cell biology, 1961
- Intercellular Attachment in the Epithelium of Hydra As Revealed by Electron MicroscopyThe Journal of cell biology, 1959