THE EFFECT OF ATROPINE UPON GASTRIC SECRETION AFTER HISTAMINE STIMULATION
Open Access
- 1 October 1930
- journal article
- research article
- Published by American Society for Clinical Investigation in JCI Insight
- Vol. 9 (2), 319-332
- https://doi.org/10.1172/jci100307
Abstract
Curves are presented comparing the course of gastric secretion after histamine with that after histamine and atropine [in 7 patients]. The volume of secretion, titratable acidity, concentration of pepsin, total output of acid and total output of pepsin have been studied. Atropine dissociates the normal response to histamine, producing a marked decrease in the volume of secretion, and in the concentration and total output of pepsin. The titratable acidity rises as a result of the only slight inhibitory effect of atropine on the total output of acid. The results suggest that water, acid and pepsin may have different mechanisms of secretion.This publication has 4 references indexed in Scilit:
- THE DIAGNOSTIC VALUE·OF DETERMINATIONS OF PEPSIN IN GASTRIC JUICEJCI Insight, 1930
- QUANTITATIVE MEASUREMENTS OF PEPSIN IN GASTRIC JUICE BEFORE AND AFTER HISTAMINE STIMULATIONJCI Insight, 1929
- A QUANTITATIVE METHOD FOR THE ESTIMATION OF PEPSINJCI Insight, 1929
- The vasodilator action of histamine and of some other substancesThe Journal of Physiology, 1918