Perfusion of Gat Kidneys from Heart-Lung Circuits.

Abstract

Summary The cat kidney, perfused at constant temperature and pressure from a heart-lung circuit, provides a valuable isolated kidney preparation of high sensitivity to hormones (1,4,6,7). The isolated preparation maintains a constant oxygen uptake despite change in RBF whereas the kidney in situ maintains a constant A-V oxygen difference. The autoregulative capacity of the perfused organ varies from one preparation to the next; the responses given to physiological concentrations of hormones do not.