Some observations on the oxidative degradation of pteroyl-l-glutamic acid
- 1 February 1957
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 65 (2), 209-211
- https://doi.org/10.1042/bj0650209a
Abstract
When pteroyl-L-glutamic acid is incubated with xanthine oxidase and methylene blue it is oxidized to 2-amino-4-hydroxypteridine-6-carboxylic acid. This reaction proceeds by the dehydrogenation and hydrolysis of pteroyl-L-glutamic acid to 2-amino-4-hydroxypteridine-6-aldehyde which is then oxidized by the enzyme to 2-amino-4-hydroxypteridine-6-carboxylic acid.Keywords
This publication has 10 references indexed in Scilit:
- Pteridines from Drosophila. I. Isolation of a Yellow Pigment1Journal of the American Chemical Society, 1954
- The haemopoietic activity of folic acid treated with xanthine oxidase.1952
- Paper chromatography of some synthetic pteridinesJournal of the American Pharmaceutical Association (Scientific ed.), 1950
- Über ein fermentatives Abbauprodukt der PteroylglutaminsäureCellular and Molecular Life Sciences, 1950
- 2-Amino-4-hydroxy-6-formylpteridine, an inhibitor of purine and pterine oxidasesBiochimica et Biophysica Acta, 1950
- Vitamin B14 and Cell ProliferationScience, 1949
- PTERINE OXIDASE1949
- INHIBITION OF XANTHINE OXIDASE AND RELATED ENZYMES BY 6-PTERIDYL ALDEHYDEJournal of Biological Chemistry, 1948
- ENZYMIC TRANSFORMATION OF PTEROYLGLUTAMIC ACIDJournal of Biological Chemistry, 1948
- The Structure of the Liver L. casei FactorJournal of the American Chemical Society, 1948