TOTAL BODY WATER IN THE DOG

Abstract

Urea and sulfanilamide given intravenously to normal unanesthetized dogs, approach equilibrium between blood and tissues in about 1 hr. Linear extrapolation gives the available water for solution of the 2 compounds; both avg. 65-66% of the body wt. Direct evidence that the water available for solution of sulfanilamide is equal to total body water was obtained on 5 dogs by subsequent desiccation of the entire body.