Influence of Desoxycorticosterone Acetate and Cortisone Acetate on Body Weight of Chick Embryos.

Abstract

A retardation of body weight increase in White Leghorn chick embryos was obtained by injecting either desoxycorticosterone acetate or cortisone acetate into the yolk sac at 6 days of incubation and observing the effect on day 18. Desoxycorticosterone acetate depressed body weight increase at a dosage level of 025 mg per egg, whereas 0.5 mg of cortisone acetate was required to induce the same effects. Sesame oil alone had no effect. The effect on body weight occurred without inducing abnormalities.