Optical multiple chemical sensing: status and current challenges
- 1 January 2007
- journal article
- Published by Royal Society of Chemistry (RSC) in The Analyst
- Vol. 132 (6), 507-511
- https://doi.org/10.1039/b702753b
Abstract
Multiple optical sensors for chemical species are sensitive, non-toxic and non-invasive and enable spatially and temporally resolved multianalyte detection. Recent advances are highlighted with a focus on fluorescence-based methods and the biologically and clinically important analytes oxygen, pH, carbon dioxide and temperature. Indicator chemistries such as permeation-selective microbeads and nanoparticles allow the production of microscopically homogeneous sensor layers. The use of combinations of spectral discrimations along with time-resolved monitoring schemes based on luminescence lifetime or intensity-lifetime ratios enables all-optical real-time multianalyte determination.Keywords
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