Normal and Experimental Growth of Rat Mammary Gland.
- 1 August 1959
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 101 (4), 788-790
- https://doi.org/10.3181/00379727-101-25096
Abstract
Daily administration of 1 jjg estradiol benzoate (EB) and 2 mg progesterone (P) to mature ovariectomized rats for 19 days resulted in mammary gland growth (mean total DNA/100 g) comparable to that of rats pregnant 18-20 days. Increasing the progesterone level to 10 mg daily has little further beneficial effect on mammary gland growth. Variability in growth of experimentally developed gland was less than that of pregnant controls. Total DNA appears to be a more reliable index of mammary gland growth when expressed as unit body weight.Keywords
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