The tyrosine repressor negatively regulates aroH expression in Escherichia coli
Open Access
- 1 June 1991
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 173 (12), 3930-3932
- https://doi.org/10.1128/jb.173.12.3930-3932.1991
Abstract
The levels of the tryptophan-sensitive isoenzyme of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase of Escherichia coli, encoded by the aroH gene, were elevated in tyrR and/or trpR mutants. The effect of tyrR and trpR lesions on aroH expression was confirmed by using a lacZ reporter system. The mutational elimination of either repressor led to a threefold increase in beta-galactosidase.Keywords
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