A Functionalized, Deep Cavitand Catalyzes the Aminolysis of a Choline Derivative
- 28 May 2004
- journal article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 126 (24), 7424-7425
- https://doi.org/10.1021/ja049074r
Abstract
The aminolysis of choline p-nitrophenyl carbonate is catalyzed with turnover by a deep cavitand bearing an introverted pyridone function. The synergy of action between the recognition of the guest in the binding pocket and the catalytic activity brought to bear by the pyridone is responsible for the high substrate specificity observed.Keywords
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