ANALYSIS OF BIOLOGICAL AND IMMUNOLOGICAL ACTIVITIES IN THE TWO POOLS OF LH RELEASED DURING CONSTANT INFUSION OF LUTEINIZING HORMONE-RELEASING HORMONE (LHRH) IN MEN
- 1 September 1977
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 45 (3), 605-608
- https://doi.org/10.1210/jcem-45-3-605
Abstract
In response to constant infusion of a submaximal dose of LHRH (0.2 ug/min for 4 hours), luteinizing hormone (LH) was released in a biphasic pattern in 6 normal men. When the in vitro biologic activity of plasma LH was compared to the immunologic activity throughout the response to LHRH, the B/I ratio remained unchanged (3.6 ± 0.5, mean ± SE). Thus, in men the biologic activity of stored LH (acutely releasable) is not different from the presumably newly synthesized hormone that is released as the second pool during prolonged LHRH infusion.Keywords
This publication has 3 references indexed in Scilit:
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- Secretion Rates of LH and FSH During Infusion of LH-FSH/RH in Normal Women and in Patients with Secondary Amenorrhea: Suggestive Evidence for Two Pools of LH and FSHJournal of Clinical Endocrinology & Metabolism, 1976
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