Maintenance of the Mammary Gland in Hypophysectomized-Oophorectomized Rats by Injections of Prolactin

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Abstract
The levels of nitrogen, ribonucleic acid, deoxyribonucleic acid, β-glucuronidase activity, alkaline phosphatase activity, glutamic-aspartic transaminase activity and succinic oxidase activity were determined in mammary tissue taken from normal rats, rats that had been hypophysectomized and oophorectomized (doubly operated), and doubly operated rats injected with prolactin. Injections of the hormone into the doubly operated rats did not maintain the normal balance of these various constituents, but was found to affect the different constituents in specific ways.