Influence of Local Chemical Change on Ventilatory Stimulus From the Legs During Exercise

Abstract

Experiments on normal humans are presented which were designed to study the effect of graded local chemical change in the legs on the ventilatory response to exercise. The ventilatory stimulus from proprioceptive ventilatory receptors is augmented by local chemical change which occurs in the extremities during exercise. The strength of the stimulus is proportional to the degree of physicochemical change. Submitted on May 28, 1956