Metabolic Effects of Alcohol on the Liver

Abstract

IT is well known that the chronic or excessive ingestion of alcohol is associated with derangements in liver function and the development of liver disease. Nevertheless, the exact mechanisms whereby the intake of alcohol produces a fatty liver or Laennec's cirrhosis have remained unclear.In the past considerable emphasis has been placed on the role of the impairment of nutrition as a major factor in the development of liver disease in the alcoholic subject. Many patients afflicted with alcoholism suffer from poor nutrition, and often their consumption of the ordinary and important foodstuffs is inversely related to the magnitude of . . .