A FACTOR THAT STIMULATES RNA SYNTHESIS BY PURIFIED RNA POLYMERASE
- 1 May 1969
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 63 (1), 168-174
- https://doi.org/10.1073/pnas.63.1.168
Abstract
A protein factor, partially purified from E. coli, can stimulate some 30- to 50-fold the transcription of DNA by purified RNA polymerase. Evidence is presented suggesting that this stimulatory factor (designated M factor) exerts its effect before the RNA synthesis is initiated. The M factor is prepared from a crude ribosome fraction, but it does not require the presence of ribosomes for full activity.Keywords
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