Histological Correlation of Microcalcifications in Breast Biopsy Specimens
Open Access
- 1 July 1999
- journal article
- clinical trial
- Published by American Medical Association (AMA) in Archives of Surgery
- Vol. 134 (7), 712-716
- https://doi.org/10.1001/archsurg.134.7.712
Abstract
SINCE 1949, WHEN Leborgne1 first demonstrated that calcifications seen on breast roentgenograms were associated with cancer, microcalcifications (MCs) have become established as one of the earliest mammographically detectable changes associated with ductal carcinoma in situ (DCIS) and invasive breast cancer (IC).1-5 Microcalcifications are the primary indication for approximately 50% of the breast biopsies performed for nonpalpable mammographic abnormalities.6Figure 1 illustrates malignant-appearing MCs detected by mammography.Keywords
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