Partitioning of Amino Acid Side Chains into Lipid Bilayers: Results from Computer Simulations and Comparison to Experiment
Open Access
- 16 April 2007
- journal article
- research article
- Published by Rockefeller University Press in The Journal of general physiology
- Vol. 129 (5), 371-377
- https://doi.org/10.1085/jgp.200709745
Abstract
The free energy of partitioning an amino acid side chain from water into the cell membrane is one of the critical parameters for understanding and predicting membrane protein stability, and understanding membrane protein function. Transmembrane segments are generally very hydrophobic, but mayKeywords
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