Peroxidation and Lysosomes in Nutritional Muscular Dystrophy of Chicks.

Abstract

Summary Muscle tissues of chicks with nutritional muscular dystrophy produced by feeding a diet deficient in Vit. E and sulfur amino acids and stressed with excess dietary linoleic acid showed significant increases in per oxidation as evidenced by TBA index and also showed increased activities of the lysosomal enzymes. Addition of DL-methionine or d-a-tocopheryl acetate to the deficient diet prevented the dystrophy, reduced the peroxidation and reduced the lysosomal enzyme activities.