The Radiation-Sensitizing Effects of N-Ethylmaleimide and Iodoacetic Acid on a Radiation-Resistant Micrococcus
- 1 August 1963
- journal article
- research article
- Published by JSTOR in Radiation Research
- Vol. 19 (4), 593-+
- https://doi.org/10.2307/3571479
Abstract
The sulfhydryl group combining agents, N-ethylmaleimide (NEM) and iodoacetic acid (IAA), were investigated for their abilities to enhance gamma-radiation inactivation of Micrococcus radiodurans. At the nontoxic level of 100 /xM, inactivation by irradiation was accelerated with IAA, but no effect observed with NEM. The removal of oxygen did not produce any detectable changes in the action of either chemical. The accelerated radiolethal effect appears to be due to the highly reactive radiolytic products of IAA and their nonspecific reactions with various cellular constituents.Keywords
This publication has 4 references indexed in Scilit:
- The Effect of N-Ethylmaleimide on the Radiation Sensitivity of BacteriaJournal of General Microbiology, 1961
- UTILIZATION OF CARBOHYDRATES AND AMINO ACIDS BY MICROCOCCUS RADIODURANSCanadian Journal of Microbiology, 1960
- ULTRAVIOLET EXPOSURE STUDIES ON A GAMMA RADIATION RESISTANT MICROCOCCUS ISOLATED FROM FOODa,b,c,Journal of Food Science, 1959
- THE EFFECT OF X-RAYS ON THE SURVIVAL OF BACTERIA AND YEASTJournal of Bacteriology, 1956