Inhibition of aflatoxin B1 carcinogenesis in rainbow trout by flavone and indole compounds
- 1 January 1984
- journal article
- research article
- Published by Oxford University Press (OUP) in Carcinogenesis: Integrative Cancer Research
- Vol. 5 (5), 615-619
- https://doi.org/10.1093/carcin/5.5.615
Abstract
A calmodulin antagonist, N-(6-aminohexyl)-5-chloro-lnaphthalenesulfonamide (W-7) markedly inhibited the promoting activity of teleocidin on formation of skin tumors in mice initiated by 7,12-dimethylbenz[a]anthracene. This result strongly indicates that the critical action of the Ca2+-calmodulin system is responsible for tumor promotion in mouse skin.This publication has 17 references indexed in Scilit:
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