A Critical Examination of Resolution Equations for Gas-Liquid Chromatography: I. Generalized Equations for Linear Elution Conditions

Abstract

The various resolution expressions that have been derived from the experimental equation [R = 2(t_R2 − t_R1)/(w, + w₂] are critically evaluated. A new and generalized expression which centers attention on the component with the longer retention time is presented, assuming sample size effects and extra column factors are absent. The equation is basically a modification of the Purnell equation and can be used for both closely spaced and widely spaced components. A new chromatographic factor, the peak width ratio, is introduced. The importance of this factor is explored for both small and large capacity factors and for various regions of the HETP vs. velocity curve.