Tracing conformational changes in proteins
Open Access
- 1 January 2010
- journal article
- Published by Springer Nature in BMC Structural Biology
- Vol. 10 (Suppl 1), S1
- https://doi.org/10.1186/1472-6807-10-s1-s1
Abstract
Many proteins undergo extensive conformational changes as part of their functionality. Tracing these changes is important for understanding the way these proteins function. Traditional biophysics-based conformational search methods require a large number of calculations and are hard to apply to large-scale conformational motions.Keywords
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