PREPARATION AND PROPERTIES OF TYPE-SPECIFIC M ANTIGEN ISOLATED FROM A GROUP A, TYPE 1 HEMOLYTIC STREPTOCOCCUS
Open Access
- 1 July 1952
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 96 (1), 71-82
- https://doi.org/10.1084/jem.96.1.71
Abstract
Type-specific M antigen was extracted by heating type 1 group A streptococci at pH 2 in a boiling water bath. The protein was then purified by digestion with a preparation of crystalline ribonuclease which was free of proteolytic activity. It was further purified by fractional precipitation with (NH4)2SO4.Keywords
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