A short and stereoselective synthesis of the carbapenem antibiotic PS-5
- 1 January 1981
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 8,p. 2228-2232
- https://doi.org/10.1039/p19810002228
Abstract
The benzyl ester (3) and p-nitrobenzyl ester (PNB ester)(4) of the antibiotic PS-5 and the bis-protected PS-6 (5) were stereoselectively synthesised by application of the new carbon–carbon bond formation reaction at the C-4-position of 4-acetoxy-3-ethyl- or 4-acetoxy-3-ethyl- or 4-acetoxy-3-isopropyl-azetidin-2-ones [(10) or (11)].This publication has 4 references indexed in Scilit:
- Structure and stereochemistry of antibiotic PS-5.The Journal of Antibiotics, 1980
- PS-5, a new .BETA.-lactam antibiotic. II. Antimicrobial activity.The Journal of Antibiotics, 1979
- PS-5, a new .BETA.-lactam antibiotic. I. Taxonomy of the producing organism, isolation and physico-chemical properties.The Journal of Antibiotics, 1979
- Darstellung und Wirkungen von Acetyl‐Derivaten des CysteaminsEuropean Journal of Inorganic Chemistry, 1951