Structure-Based Design, Synthesis, and Structure−Activity Relationship Studies of Novel Non-nucleoside Adenosine Deaminase Inhibitors
- 17 June 2004
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 47 (15), 3730-3743
- https://doi.org/10.1021/jm0306374
Abstract
No abstract availableKeywords
This publication has 24 references indexed in Scilit:
- Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damageNature, 2001
- Sites of action for future therapy: an adenosine-dependent mechanism by which aspirin retains its antiinflammatory activity in cyclooxygenase-2 and NFκB knockout miceOsteoarthritis and Cartilage, 1999
- Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settingsAdvanced Drug Delivery Reviews, 1997
- The antiinflammatory mechanism of methotrexate. Increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vivo model of inflammation.Journal of Clinical Investigation, 1993
- Structure-Based Design of a Cyclophilin-Calcineurin Bridging LigandScience, 1993
- AMoRE, an integrated molecular replacement program in protein crystallography: some applications to multibody systemsActa Crystallographica Section A Foundations of Crystallography, 1993
- Direct Association of Adenosine Deaminase with a T Cell Activation Antigen, CD26Science, 1993
- The osmium-catalyzed asymmetric dihydroxylation: a new ligand class and a process improvementThe Journal of Organic Chemistry, 1992
- Neuroprotective role of adenosine in cerebral ischaemiaTrends in Pharmacological Sciences, 1992
- Pharmacokinetics of inhibition of adenosine deaminase by erythro-9-(2-hydroxy-3-nonyl)adenine in CBA miceBiochemical Pharmacology, 1982