Cyclin B‐dependent kinase and caspase‐1 activation precedes mitochondrial dysfunction in fumarylacetoacetate‐induced apoptosis
- 1 December 1999
- journal article
- Published by Wiley in The FASEB Journal
- Vol. 13 (15), 2284-2298
- https://doi.org/10.1096/fasebj.13.15.2284
Abstract
Hereditary tyrosinemia type I is the most severe metabolic disease of the tyrosine catabolic pathway mainly affecting the liver. It is caused by deficiency of fumarylacetoacetate hydrolase, which p...Keywords
Funding Information
- Medical Research Council Canada (MT‐11086)
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