Biomarker selection for medical diagnosis using the partial area under the ROC curve
Open Access
- 1 January 2014
- journal article
- Published by Springer Nature in BMC Research Notes
- Vol. 7 (1), 25
- https://doi.org/10.1186/1756-0500-7-25
Abstract
A biomarker is usually used as a diagnostic or assessment tool in medical research. Finding an ideal biomarker is not easy and combining multiple biomarkers provides a promising alternative. Moreover, some biomarkers based on the optimal linear combination do not have enough discriminatory power. As a result, the aim of this study was to find the significant biomarkers based on the optimal linear combination maximizing the pAUC for assessment of the biomarkers.Keywords
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