A Controlled Clinical Trial of Methylpentynol (“Oblivon”)

Abstract

There have been many new types of sedatives and hypnotics evolved in recent years. The term “tranquillizing drug” is a recent innovation which suggests a calming effect without a hypnotic effect. Methylpentynol (“Oblivon”) is one such drug which has little hypnotic action, but is said specifically to relieve anxiety. This action was noted by the relief of apprehension observed in patients prior to dental treatment (Trotter, 1953). Methylpentynol is a higher alcohol which in high dosage has a hypnotic effect in animals (Margolin et al., 1951). No toxic effects have been reported. It is made up in rather large, blue-green capsules containing 250 mg. of methylpentynol, and also as an elixir.